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The Best Episodes of Grey's Anatomy Season 22

Every episode of Grey's Anatomy Season 22 ranked from best to worst. Discover the Best Episodes of Grey's Anatomy Season 22!

Binge this in 8h 45mPeaking at 8.4/10

Follows the personal and professional lives of a group of doctors at Seattle's Grey Sloan Memorial Hospital.

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Episode Rankings

  1. #1 Fan Favorite
    Grey's Anatomy Season 22 Episode 1 - Only the Strong Survive
    8.1/10(360 votes)

    #1 - Only the Strong Survive

    S22:E1

    After the catastrophic hospital explosion, Grey Sloan's staff scrambles to save not only their patients' lives but also their own. Confronted with impossible surgical decisions and emotional turmoil, they fight to preserve life amid devastation.

    Director:Debbie Allen

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  2. Grey's Anatomy Season 22 Episode 2 - We Built This City
    7.4/10(267 votes)

    #2 - We Built This City

    S22:E2

    The team at Grey Sloan navigates a chaotic first day of surgical rotations amid hospital renovations. Meanwhile, Meredith spends time with Amelia.

    Director:Kevin McKidd

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  3. Grey's Anatomy Season 22 Episode 3 - Between Two Lungs
    7.3/10(246 votes)

    #3 - Between Two Lungs

    S22:E3

    A high-risk lung transplant pushes the surgical team to their limits. Meanwhile, Bailey juggles a trauma patient whose treatment hangs in the balance.

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  4. Grey's Anatomy Season 22 Episode 4 - Goodbye Horses
    7.2/10(224 votes)

    #4 - Goodbye Horses

    S22:E4

    The interns juggle a bizarre trauma, while a complex breast reconstruction forces Meredith into a tense partnership.

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  5. Grey's Anatomy Season 22 Episode 5 - Sometimes I Feel Like a Motherless Child
    7.6/10(226 votes)

    #5 - Sometimes I Feel Like a Motherless Child

    S22:E5

    Jo navigates a challenging case with a pregnant mother, while Blue and Jules care for a diabetic patient. Meanwhile, Simone treats a patient with a surprising revelation.

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  6. Grey's Anatomy Season 22 Episode 6 - When I Crash
    7.7/10(226 votes)

    #6 - When I Crash

    S22:E6

    Grey Sloan takes in patients following a catastrophic bus accident. Teddy and Owen have an awkward encounter, and Richard tests Bailey's patience.

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  8. Grey's Anatomy Season 22 Episode 7 - Skyfall
    7.5/10(200 votes)

    #7 - Skyfall

    S22:E7

    Winston and Ben fight to save Jo's life, while Teddy supports Link. Owen and Jules battle to save a young man, and Lucas forms an unexpected bond with a patient.

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  9. Grey's Anatomy Season 22 Episode 8 - Heavy on Me
    7.6/10(178 votes)

    #8 - Heavy on Me

    S22:E8

    Bailey and Owen join forces to save a tumor patient, while Richard faces an internal battle. Meanwhile, Jules struggles with her feelings for Winston.

    Director:Lisa Leone

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  10. Grey's Anatomy Season 22 Episode 9 - Fortunate Son
    7.2/10(170 votes)

    #9 - Fortunate Son

    S22:E9

    Richard continues to navigate his health. Meanwhile, Meredith and Nick are visited by Nick's estranged sister from Boston.

    Director:Kim Raver
    Writer:Julie Wong

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  11. Grey's Anatomy Season 22 Episode 10 - Strip That Down
    7.7/10(160 votes)

    #10 - Strip That Down

    S22:E10

    Addison Montgomery returns to Grey Sloan, seeking assistance with a patient with a neurological condition. Bailey joins Owen and Blue on a paramedic ride-along.

    Director:Kevin McKidd

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  12. Grey's Anatomy Season 22 Episode 11 - (If You Want It) Do It Yourself
    7.9/10(118 votes)

    #11 - (If You Want It) Do It Yourself

    S22:E11

    Teddy and Winston clash over a case, while Owen and Jules treat a urologist. Lucas struggles with prioritizing patients.

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  13. Grey's Anatomy Season 22 Episode 12 - Get Lucky
    8.4/10(51 votes)

    #12 - Get Lucky

    S22:E12

    Tensions rise as Teddy and Winston take on a complex procedure, while Kavita and Ben try and impress the new plastics attending. Jo and Link leave the babies with a nanny for the first time.

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Season 22 Ratings Summary

"Only the Strong Survive" is the best rated episode of "Grey's Anatomy" season 22. It scored 8.1/10 based on 360 votes. Directed by Debbie Allen and written by Meg Marinis, it aired on 10/9/2025. This episode is rated 0.7 points higher than the second-best, "We Built This City".