The Best Episodes of Grey's Anatomy Season 1

Episode Rankings

1. #1 Fan Favorite
   

   8.3/10(3602 votes)

   #1 - A Hard Day's Night

   S1:E13/27/2005

   Meet Meredith Grey. Daughter of famous surgeon Ellis Grey and currently recovering from a one-night stand. She shoos away her evening's companion, saying she'll be late for her first day of work. She is a first year intern at Seattle Grace Hospital and is working alongside some colorful characters. Cristina Yang is a highly competitive Stanford graduate who befriends Meredith. George O'Malley is a quirky warm hearted man who learns a lesson or two on his first day. Izzie Stevens is a former model who doesn't get any special treatment on her first day. And Alex Karev is an arrogant jerk who misdiagnoses a patient on his first shift. Overseeing them is Miranda Bailey, (not-so-) affectionately dubbed 'The Nazi'. Meredith also gets a surprise when she realizes that her friend from the night before is a co-worker, and even worse, her boss.

   Director:Peter Horton

   Writer:Shonda Rhimes

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   Director:Peter Horton

   Writer:Shonda Rhimes
2. 

   8.1/10(2494 votes)

   #2 - The First Cut is the Deepest

   S1:E24/3/2005

   The surgical staff tries to be optimistic as a young woman clings to life after a brutal attack. Meanwhile Meredith puts her career on the line to save a newborn in the hospital nursery, and the other interns learn that it takes more than just medical knowledge to be good at their jobs.

   Director:Peter Horton

   Writer:Shonda Rhimes

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   Director:Peter Horton

   Writer:Shonda Rhimes
3. 

   8.0/10(2309 votes)

   #3 - Winning a Battle, Losing the War

   S1:E34/10/2005

   A bike race injures several pedestrians as well as well as participants. One pedestrian is left brain dead. Christina and Issie wish to use his organs for organ donation but with Christina's detachment and Issie's ever hopeful attitude that the man will recover, they will find the organ harvesting process an emotional one. Preston faces feelings of his dislike of organ harvesting - as a surgeon, he likes saving lives; harvesting organs doesn't save the person's life. George deals with Mac, a friend of the chief, who won't stop flirting with him. He is in need of a new liver. Meredith is fed up with Alex showing off as she continues trying to push Derek away. She also is reaching the limits of Issie's sunshine and George's politeness as she goes on living with them. Then there is their desire to see Meredith's mother's medical tapes. Getting through the day, Meredith realizes the keys to winning the race.

   Director:Tony Goldwyn

   Writer:Shonda Rhimes

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   Director:Tony Goldwyn

   Writer:Shonda Rhimes
4. 

   8.0/10(2175 votes)

   #4 - No Man's Land

   S1:E44/17/2005

   While George is feeling a little less masculine because of the way Izzie and Meredith have been treating him (like a sister), Izzie is assigned to a patient about to loose all of his masculinity. Cristina, true to her competitive spirit, shows up early and assigns herself to an ill woman, who happens to have been Meredith's moms scrub nurse. Alex, meanwhile, is busying himself copying and pasting pictures of Izzie's racy magazine spread all over the interns' locker room. And while Meredith is trying to cope with her mother's Alzheimer's, Derek treats a patient who has managed to get nails stuck in his head.

   Director:Adam Davidson

   Writer:James D. Parriott

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   Director:Adam Davidson

   Writer:James D. Parriott
5. 

   8.0/10(2096 votes)

   #5 - Shake Your Groove Thing

   S1:E54/24/2005

   Meredith realizes that she must take on a lot more responsibility when she is told that her mother needs to sign over all of her assets to her. As Izzie prepares to have a party for her boyfriend Hank (the scale of which is unknown to Meredith), Meredith has her first heart surgery. During the surgery she fears that she has fallen asleep and damaged the patient's heart. Meanwhile, Cristina and Burke hit it off. At the party, Meredith and Derek get caught together by Dr. Bailey.

   Director:John David Coles

   Writer:Ann Lewis Hamilton

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   Director:John David Coles

   Writer:Ann Lewis Hamilton
6. 

   8.1/10(2019 votes)

   #6 - If Tomorrow Never Comes

   S1:E65/1/2005

   Izzie tries to get George to find the courage to ask Meredith out. All of the interns are in awe when a woman comes in with a record breaking tumor, but it is so far advanced that the woman's prognosis is not good. Now that Bailey knows about Meredith and Derek's affair, their jobs are in jeopardy, and she advises Meredith to end it. Meanwhile, Cristina and Burke's secret relationship is also getting more complicated...

   Director:Scott Brazil

   Writer:Krista Vernoff

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   Director:Scott Brazil

   Writer:Krista Vernoff
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7. 

   8.1/10(1993 votes)

   #7 - The Self-Destruct Button

   S1:E75/8/2005

   Derek and Meredith try (unsuccessfully) to be discreet as they spend the night together at Meredith's house, but their haggard appearance speaks volumes to everyone - including Bailey, who warns Meredith to end the relationship. Meanwhile George suspects an anesthesiologist of drinking on the job but is reluctant to speak up about it, Alex treats a former competitor who now finds honor in self-mutilation, Izzie has to deal with a patient who won't let go of his girlfriend - literally, and Cristina seems to be battling a case of the flu.

   Director:Darnell Martin

   Writer:Kip Koenig

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   Director:Darnell Martin

   Writer:Kip Koenig
8. 

   7.9/10(1968 votes)

   #8 - Save Me

   S1:E85/15/2005

   Meredith grows increasingly dissatisfied with the unknown details of Derek's life. Meanwhile, Alex treats Devo, a patient whose religious beliefs jeopardize her chances for recovery; Izzie contemplates reconnecting with her estranged mother; Zoey, a pregnant woman in her 40s who's been diagnosed with cancer, disagrees with Cristina's medical advice; and the interns are mystified by Cable, a patient who's being treated for seizures and who thinks he's psychic.

   Director:Sarah Pia Anderson

   Writer:Mimi Schmir

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   Director:Sarah Pia Anderson

   Writer:Mimi Schmir
9. 

   8.6/10(2226 votes)

   #9 - Who's Zoomin' Who?

   S1:E95/22/2005

   A sexually transmitted disease breaks out and affects several members of the hospital staff. Chief Webber promptly calls a meeting. Meanwhile, the chief reluctantly tells Dr. Derek Shepherd about his own medical concerns. Izzie and Cristina worry about a patient's wife and daughter who can't agree on his care. Burke treats his college buddy Bill, whose medical diagnosis raises some questions regarding his wife's actions. Then just as Meredith and Derek grow more intimate, a surprise is revealed.

   Director:Wendey Stanzler

   Writers:Harry Werksman, Gabrielle Stanton

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   Director:Wendey Stanzler

   Writers:Harry Werksman, Gabrielle Stanton