Stan tries an experimental pill from the CIA and turns into a girl. Meanwhile, Klaus and Roger start a business selling Stan's suits as he no longer needs them as a female.

American Dad becomes the 25th scripted primetime show in the History of Television to reach 300 episodes and Roger's past comes back to haunt him.

Francine and Stan swap spouses with their gay neighbours Terry and Greg when Terry's dad, a former football player who doesn't know that his son is gay, arrives for a visit. Meanwhile, Steve goes on a drunken bender.

Steve is upset when Snot threatens their summer camp fun by becoming a counselor-in-training. Meanwhile, Hayley and Jeff become suspicious of Roger when he organizes a "Burning Man" reenactment for their anniversary.

Stan's co-workers at the CIA teach him about "rubbernecking," the art of checking out other women on the sly, away from the gaze of their wives. But when Stan causes a massive accident in an attempt to take a picture of an attractive jogger, he's interviewed by an intimidating insurance inspector who may rat out Stan to Francine. Meanwhile, Roger and Klaus spill wine on the Smiths' brand new couch, and vow never to tell the other family members by sitting on the stained spot for the rest of their lives.

Jeff wins a tour through a mysterious weed factory and brings Stan along.

Steve becomes a pilot.

Steve and his friends take up witchcraft to gain power and popularity at school. Stan and Klaus become obsessed with remembering 90s bands.

Bullock throws a private, star-studded Christmas party the exact same night as the CIA work party. Stan and Klaus are determined to get in, by any means necessary.

Stan uses a mothballed military computer to do Steve's math homework, starting the clock toward nuclear annihilation.

Thanks to Roger, Snot discovers his dead father was a demolition derby driver. Hayley takes Steve on a road trip, so he can learn to drive.

When the family goes to a dude ranch, Klaus and Rogu have to work together to survive in the wilderness.

Francine is jealous of the new and improved Klaus and vows to take him down.

When Roger is rejected by Steve, who seems to be over him, Roger heads out in search of a new human companion. But when this new friend starts to abuse Roger and the relationship turns into a lot of excuses and sorry's, Steve and Hayley scheme to get Roger out of the bad relationship and back home where he belongs. Meanwhile, Stan tours the Mr. Pibb factory and meets the man himself.

Stan can't escape a recurring Father's Day.

The Smith family must rescue Steve after he is kidnapped and taken to the North Pole. There, Santa Claus is using children to mine for precious stones that he needs to perform an ancient ritual.

Steve becomes the town pariah after he convinces the star quarterback of the Bazooka Sharks arena football team to stop playing. Meanwhile, Roger forces Hayley to become a cab driver to pay him back for her gambling debts.

The family competes on the reality show, The Bitchin' Race but after Stan and Hayley ditch the less-motivated Steve and Francine to team up, they end up in a Tunisian labor prison.

Roger and Klaus start having a secret affair after they accidentally end up on an online date together. Meanwhile, Steve tries to catch Hayley's pink eye to get out of doing a fitness test at school.

Stan becomes a wanted man, running from Roger the bounty hunter, and ends up in a town in need of a good guy to help Principal Lewis, Francine, Steve and Hayley.

Stan and Hayley compete in collecting data for the US Census; Klaus has Steve and his friends model for his new camera.

Klaus enlists Stan, Roger and Jeff to join him on a wild bachelor party weekend.

After a series of boring personas, Roger goes to great lengths to prove to Francine he still has "his edge".

Stan tries a new, cutting edge parenting approach DNA splicing.

Stan has his heart set on speaking at the Republican National Convention on behalf of the Langley chapter, but when they pass him up for another candidate, he accepts the only endorsement he gets from the local chapter of Gay Republicans. While the people around him disapprove of his new lifestyle choice, Stan decides to follow his heart to speak on their behalf.