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The Worst Episodes of Mystery Diagnosis

Every episode of Mystery Diagnosis ranked from worst to best. Explore the Worst Episodes of Mystery Diagnosis!

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Mystery Diagnosis is a television program that airs on the OWN: Oprah Winfrey Network. Each episode focuses on two or more individuals and their struggles to find out what ailments they suffer from. As the

Airs on
Discovery Health Channel
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Episode Rankings

  1. #1 Worst Episode
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    Mystery Diagnosis Season 1 Episode 1 - Grasping for Straws
    0.0/10(0 votes)

    #1 - Grasping for Straws

    S1:E1

    Doctors are baffled by a woman's mysterious respiratory problem. Featuring Cushing's syndrome, gout, carcinoid cancer.

    Director:Unknown
    Writer:Unknown

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  2. Mystery Diagnosis Season 1 Episode 2 - Like Mother, Like Son
    0.0/10(0 votes)

    #2 - Like Mother, Like Son

    S1:E2

    A child with celiac disease is intolerant of gluten; a woman has her left frontal lobe removed to stop seizures; another woman suffers from fatigue and mood swings. Featuring celiac disease, mitral valve prolapse (MVP), epilepsy.

    Director:Unknown
    Writer:Unknown

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  3. Mystery Diagnosis Season 1 Episode 3 - Not A Normal Newborn
    0.0/10(0 votes)

    #3 - Not A Normal Newborn

    S1:E3

    A child with Hurler's disease undergoes a stem-cell transplant procedure; a woman is diagnosed with myasthenia gravis; A father has seizures and fainting spells due to a heart arrhythmia. Featuring Hurler syndrome, myasthenia gravis, cardiac arrhythmia.

    Director:Unknown
    Writer:Unknown

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  4. Mystery Diagnosis Season 1 Episode 4 - Isaac's Nightmare
    0.0/10(0 votes)

    #4 - Isaac's Nightmare

    S1:E4

    A young boy's body is not producing antibodies to fight infections; a cancerous tumor must be removed; a woman loses the ability to walk. Featuring common variable immunodeficiency (CVID), gastrointestinal stromal tumor (GIST), reflex sympathetic dystrophy (RSD).

    Director:Unknown
    Writer:Unknown

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  5. Mystery Diagnosis Season 1 Episode 6 - Blood & Fire
    0.0/10(0 votes)

    #5 - Blood & Fire

    S1:E6

    A 12-year-old girl experiences abdominal pains and severe headaches until she is diagnosed with a retroflexed odontoid and Chiari One malformation; a firefighter and paramedic is diagnosed with acquired immunodeficiency syndrome (AIDS).

    Director:Unknown
    Writer:Unknown

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  6. Mystery Diagnosis Season 1 Episode 7 - Desperate for a Cure
    0.0/10(0 votes)

    #6 - Desperate for a Cure

    S1:E7

    A 5-year-old has a persistent fever and stomachache. A man crippled with a neck tilt. A woman falls ill after traveling abroad. Featuring Crohn's disease, cervical dystonia, brucellosis.

    Director:Unknown
    Writer:Unknown

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  7. Mystery Diagnosis Season 1 Episode 8 - Blood Brothers
    0.0/10(0 votes)

    #7 - Blood Brothers

    S1:E8

    Two brothers suffer the same heart problem. Joanne suffers from joint pain, mouth ulcers, genital sores, skin lesions, and vision problems. Featuring Barth Syndrome, Behcet's Disease

    Director:Unknown
    Writer:Unknown

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  8. Mystery Diagnosis Season 2 Episode 2 - An Unquenchable Thirst
    0.0/10(0 votes)

    #8 - An Unquenchable Thirst

    S2:E2

    A baby drinks excessively, projectile vomits and stops growing. A professional baseball player's wife struggles to get pregnant due to a brain tumor. An old man is robbed of his eyesight.

    Director:Unknown
    Writer:Unknown

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  9. Mystery Diagnosis Season 2 Episode 3 - Lethal Diet
    0.0/10(0 votes)

    #9 - Lethal Diet

    S2:E3

    Parents deal with a son with sinus infections and unsteady feet; a woman gains weight and has oily skin, hair loss, body cramps and irritable bowel syndrome. A reverend has trouble sleeping.

    Director:Unknown
    Writer:Unknown

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  10. Mystery Diagnosis Season 2 Episode 4 - Falling Through the Cracks
    0.0/10(0 votes)

    #10 - Falling Through the Cracks

    S2:E4

    A man has suffered from vertigo and ear infections since childhood. A 16-year-old girl has headaches and neck twitching, that led to preeclampsia. A girl has a serious heart condition and stops growing and gaining weight.

    Director:Unknown
    Writer:Unknown

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  11. Mystery Diagnosis Season 2 Episode 5 - Eaten Alive
    0.0/10(0 votes)

    #11 - Eaten Alive

    S2:E5

    A baby's hair appears brittle, and she is slow in developing after a case of whooping cough. Following a tube-tie procedure, Jackie contracted a flesh-eating disease. A boy develops nosebleeds, a sign of something much more terrifying.

    Director:Unknown
    Writer:Unknown

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  12. Mystery Diagnosis Season 2 Episode 6 - The Man Who Never Sweats
    0.0/10(0 votes)

    #12 - The Man Who Never Sweats

    S2:E6

    A baby shows signs of a genetic disorder. A college graduate developed bloating, decreased sex drive, and yellowing of the eyes. Since childhood, Scott has battled an array of symptoms—severe joint pain, strange rashes, and an inability to sweat. Could his symptoms be related to his kidneys?

    Director:Unknown
    Writer:Unknown

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  13. Mystery Diagnosis Season 2 Episode 7 - Fatal Secret
    0.0/10(0 votes)

    #13 - Fatal Secret

    S2:E7

    Roman was a baby when his parents noticed his head always tilting to one side and his eyes rolling back into his head when he looked up. Could the cause be just one condition? Sharon was an active varsity diver but after a car accident, she developed an unquenchable thirst that would soon take over her life. Peggy lived a healthy and active lifestyle, until one day when the mother of two experienced coughing, joint pain, and swelling.

    Director:Unknown
    Writer:Unknown

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  14. Mystery Diagnosis Season 2 Episode 8 - The Stabbing Sensation
    0.0/10(0 votes)

    #14 - The Stabbing Sensation

    S2:E8

    Nicky was a healthy five-year-old boy until terrifying symptoms landed him in the hospital, fighting for his life. Kristine was a super mom until crippling abdominal pains would change her life forever. Jackie was active until mysterious pains wracked her entire body, eventually becoming so bad that she had to drop out of school.

    Director:Unknown
    Writer:Unknown

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  15. Mystery Diagnosis Season 2 Episode 9 - The Man With Rocks in His Chest
    0.0/10(0 votes)

    #15 - The Man With Rocks in His Chest

    S2:E9

    A baby boy suffers from the same symptoms that killed off male offspring on his mother's side of the family, Could doctors figure out what it is before it's too late? A man in his late thirties experiences a constant, painful burning sensation in his chest, making breathing difficult, but an initial trip to the ER reveals nothing. A woman lives with joint pain, redness in her eyes, and a blood test revealed an elevated anti-nuclear antibody.

    Director:Unknown
    Writer:Unknown

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  16. Mystery Diagnosis Season 3 Episode 2 - The Man Who Turned Orange
    0.0/10(0 votes)

    #16 - The Man Who Turned Orange

    S3:E2

    A doctor makes an unexpected discovery when he operates on a young woman; doctors try to reach a diagnosis when a marathon runner experiences mysterious fatigue.

    Director:Unknown
    Writer:Unknown

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  17. Mystery Diagnosis Season 3 Episode 6 - The Boy Who Couldn't Breathe
    0.0/10(0 votes)

    #17 - The Boy Who Couldn't Breathe

    S3:E6

    A 3-month-old boy has breathing difficulties; a woman has stomach problems; stepping on a crochet hook causes strange problems for a patient.

    Director:Unknown
    Writer:Unknown

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  18. Mystery Diagnosis Season 3 Episode 7 - Frenetic Genetics
    0.0/10(0 votes)

    #18 - Frenetic Genetics

    S3:E7

    An infant shows diverse symptoms; an ER nurse gets a diagnosis of lymphoma, before another symptom reveals her true illness.

    Director:Unknown
    Writer:Unknown

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  19. Mystery Diagnosis Season 3 Episode 8 - The Baby Who Changed Colors
    0.0/10(0 votes)

    #19 - The Baby Who Changed Colors

    S3:E8

    Brenda and Jake are delighted when their daughter Isabel is born, but their euphoria quickly turns to panic when Isabel stops eating and her skin turns grey. Noah and Alexis were healthy twins until they suddenly lost all their milestones. Charlie, an active pastor, has difficulty reading; doctors must act quickly to save his eyesight.

    Director:Unknown
    Writer:Unknown

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  20. Mystery Diagnosis Season 4 Episode 1 - The Girl Who Couldn't Eat
    0.0/10(0 votes)

    #20 - The Girl Who Couldn't Eat

    S4:E1

    Doctors wonder why an apparently healthy baby fails to achieve its developmental goals; on the other hand, a woman who seemed to be in good health suddenly becomes ill.

    Director:Unknown
    Writer:Unknown

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  21. Mystery Diagnosis Season 4 Episode 2 - Bizarre Visions
    0.0/10(0 votes)

    #21 - Bizarre Visions

    S4:E2

    A woman experiences chronic stomach pain and diarrhea attributed to irritable bowel syndrome; another faces extreme fatigue and night sweating while pregnant.

    Director:Unknown
    Writer:Unknown

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  22. Mystery Diagnosis Season 4 Episode 3 - The Woman Who Craved Pickles
    0.0/10(0 votes)

    #22 - The Woman Who Craved Pickles

    S4:E3

    A baby boy could not keep any food down; an X-Ray revealed that he had been born with a diaphragmatic hernia. A woman who suffers from extreme fatigue has strange cravings for pickles; when her heart nearly stops, doctors try to find the cause of her problems.

    Director:Unknown
    Writer:Unknown

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  23. Mystery Diagnosis Season 4 Episode 4 - Donor Disaster
    0.0/10(0 votes)

    #23 - Donor Disaster

    S4:E4

    A pregnant woman experiences stomach pains and headaches; another woman experiences eye inflammation and joint stiffness.

    Director:Unknown
    Writer:Unknown

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  24. Mystery Diagnosis Season 4 Episode 5 - The Purple Puzzle
    0.0/10(0 votes)

    #24 - The Purple Puzzle

    S4:E5

    An abnormality on the ultrasound alarms parents expecting a baby; a biology teacher has a series of strange symptoms.

    Director:Unknown
    Writer:Unknown

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  25. Mystery Diagnosis Season 4 Episode 6 - A Case of Paralysis
    0.0/10(0 votes)

    #25 - A Case of Paralysis

    S4:E6

    An aspiring actress awakens to an excruciating pain on the right side of her face; Bill experiences nausea and strange tingling in his legs; doctor visits and MRI tests show how these two different cases reveal paralysis.

    Director:Unknown
    Writer:Unknown

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Worst Episodes Summary

"Grasping for Straws" is the worst rated episode of "Mystery Diagnosis". It scored /10 based on 0 votes. Directed by Unknown and written by Unknown, it aired on 3/7/2005. This episode scored 0.0 points lower than the second lowest rated, "Like Mother, Like Son".