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The Best Episodes of My Friend's Little Sister Has It In for Me!

Every episode of My Friend's Little Sister Has It In for Me! ranked from best to worst. Let's dive into the Best Episodes of My Friend's Little Sister Has It In for Me!!

Binge this in 4h 48m•Peaking at 10.0/10

For high schooler Akiteru Oboshi, the whole youthful experience thing—like fun, friendships, and even having a girlfriend—is a complete waste of time. So when his best friend’s sister, Iroha Kohinata, keeps teasing him, Akiteru naturally

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  1. #1 Fan Favorite
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    My Friend's Little Sister Has It In for Me! Season 1 Episode 3 - Only I Can Be a Pain to My Uncle’s Daughter
    10.0/10(2 votes)

    #1 - Only I Can Be a Pain to My Uncle’s Daughter

    S1:E3

    Akiteru decides to throw a welcome party for Mashiro, but first he must convince her to attend.

    Director:Unknown
    Writer:Unknown

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  2. My Friend's Little Sister Has It In for Me! Season 1 Episode 4 - My Friend's Little Sister Might Be a Delinquent
    10.0/10(2 votes)

    #2 - My Friend's Little Sister Might Be a Delinquent

    S1:E4

    Akiteru and Iroha recall how they first met.

    Director:Unknown
    Writer:Unknown

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  3. My Friend's Little Sister Has It In for Me! Season 1 Episode 6 - My Friend's Little Sister Has It In for My Friend's Enemy
    10.0/10(2 votes)

    #3 - My Friend's Little Sister Has It In for My Friend's Enemy

    S1:E6

    While at the mall with Mashiro and Iroha, Akiteru learns why Mashiro left her old school.

    Director:Unknown
    Writer:Unknown

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  4. My Friend's Little Sister Has It In for Me! Season 1 Episode 7 - The Girl Who Confessed to Me Is Cold to Me in Reality
    10.0/10(2 votes)

    #4 - The Girl Who Confessed to Me Is Cold to Me in Reality

    S1:E7

    Akiteru tries to give a proper reply to Mashiro's love confession, but she's brutally cold to him in person.

    Director:Unknown
    Writer:Unknown

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  5. My Friend's Little Sister Has It In for Me! Season 1 Episode 8 - Everyone I Know Is Being Weird With Me
    10.0/10(2 votes)

    #5 - Everyone I Know Is Being Weird With Me

    S1:E8

    Sumire asks Akiteru for help with a problem that could endanger her future with 05th Floor Alliance.

    Director:Unknown
    Writer:Unknown

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  6. My Friend's Little Sister Has It In for Me! Season 1 Episode 9 - My Fake Girlfriend Gets Tough When I Respond To Her Confession
    10.0/10(2 votes)

    #6 - My Fake Girlfriend Gets Tough When I Respond To Her Confession

    S1:E9

    Akiteru and Iroha head to Otoi's studio to record for the game, but Iroha has ideas of her own.

    Director:Unknown
    Writer:Unknown

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    7. Trending NowTRENDING NOW

    The 20 WORST Episodes of My Friend's Little Sister Has It In for Me!

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  7. My Friend's Little Sister Has It In for Me! Season 1 Episode 10 - My Friend's Little Sister Only Gets an Apology from Me
    10.0/10(2 votes)

    #7 - My Friend's Little Sister Only Gets an Apology from Me

    S1:E10

    Akiteru must clear the air with Iroha to keep 05th Floor Alliance running smoothly.

    Director:Unknown
    Writer:Unknown

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  8. My Friend's Little Sister Has It In for Me! Season 1 Episode 11 - We're Perfect for Training the Drama Club
    10.0/10(2 votes)

    #8 - We're Perfect for Training the Drama Club

    S1:E11

    With 05th Floor Alliance's help, the drama club is ready for the big competition... but then disaster strikes.

    Director:Unknown
    Writer:Unknown

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  9. My Friend's Little Sister Has It In for Me! Season 1 Episode 12 - My Friend's Little Sister Really Does Have It In for Me
    10.0/10(2 votes)

    #9 - My Friend's Little Sister Really Does Have It In for Me

    S1:E12

    Can Akiteru save the drama club and secure 05th Floor Alliance's future?

    Director:Unknown
    Writer:Unknown

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  10. My Friend's Little Sister Has It In for Me! Season 1 Episode 1 - My Friend's Little Sister Has It In for Me
    9.0/10(3 votes)

    #10 - My Friend's Little Sister Has It In for Me

    S1:E1

    Akiteru just wants to work toward his future, but his friend's little sister won't allow him any peace.

    Director:Kazuomi Koga
    Writer:Touko Machida

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  11. My Friend's Little Sister Has It In for Me! Season 1 Episode 2 - The Cousin I Haven't Seen in Years Is Cold to Me
    9.0/10(3 votes)

    #11 - The Cousin I Haven't Seen in Years Is Cold to Me

    S1:E2

    Now that Mashiro has moved to his school, can Akiteru manage to make her open up to him?

    Director:Unknown
    Writer:Unknown

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  12. My Friend's Little Sister Has It In for Me! Season 1 Episode 5 - My Friend's Little Sister Keeps Getting Close to Me
    9.0/10(2 votes)

    #12 - My Friend's Little Sister Keeps Getting Close to Me

    S1:E5

    A look back at how Iroha came to be the voice actress for 05th Floor Alliance.

    Director:Unknown
    Writer:Unknown

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Best Episodes Summary

"Only I Can Be a Pain to My Uncle’s Daughter" is the best rated episode of "My Friend's Little Sister Has It In for Me!". It scored 10/10 based on 2 votes. Directed by Unknown and written by Unknown, it aired on 10/18/2025. This episode scored 0.0 points higher than the second highest rated, "My Friend's Little Sister Might Be a Delinquent".