Murdoch investigates a car accident and uncovers sinister motives.

Murdoch discovers his passion for canines while investigating the death of a championship show dog.

A jailed Murdoch must prove his innocence amid police and government corruption after the constables are ambushed, Ogden is kidnapped, and Brackenreid goes missing.

Murdoch investigates the claims of a man who says his time travels to the future provided him with information that allowed him to stop crimes, while the New Year's Eve Policeman's Ball offers exciting personal possibilities for the 20th century.

Murdoch finds himself with amnesia and running for his life on the streets of Bristol, England, very far from home, if he knew where his home was. Taking refuge in a pub, he gains the assistance of a vivacious barmaid who helps him reconstruct his memories, escape his pursuers, and foil an assassination plot.

Workers laboring to build a bridge across the Don River make a grisly discovery – entombed in the swamplands bordering the river are the well-preserved bodies of a man and a woman. Called to the scene, Murdoch and Ogden quickly determine that the couple was murdered. When a third body is then discovered, Murdoch has to re-evaluate the nature of the crime.

Detective Murdoch is taunted by a deranged criminal who leaves talking dolls with macabre personal messages at each crime scene.

Murdoch and Brackenreid unwittingly put their careers at risk when they investigate high-level police corruption.

A family celebration of Alexander Reynolds' 60th birthday is dampened when he's found with a knife plunged into his chest. Murdoch is called in and soon discovers the victim was universally despised by his kin. Reynolds' family instantly falls under suspicion but the field of suspects narrows considerably when daughter Charlotte Reynolds appears in a blood soaked dress and confesses to killing her father.

Murdoch makes a surprising discovery at a dolls house fair; in one of the houses the artist has placed a hand firing a gun. This is no ordinary model - it’s a crime scene. Murdoch finds the creator of the streetscape, an autistic 19-year-old, Lydia, who communicates best through model building. No one has reported a murder yet, but using the model’s intricate clues left by Lydia, Murdoch discovers that someone indeed has been killed – but what happened and why? Someone is far from happy by his investigations and things begin to get even more sinister in the neighbourhood.

With his colleague sentenced to hang for murder, Detective Murdoch races to exonerate them and steps into a trap set by the real killer.

A recording device made by Alexander Graham Bell assists in the investigation of a murder at a dinner honoring Helen Keller.

Murdoch and company's Christmas at an idyllic country estate turns potentially deadly.

After a ruthless inventor is killed at a convention, Murdoch's investigation is assisted by his idol, Alexander Graham Bell.

Two bank safe deposit boxes that were being transferred are taken by thieves and the crime is investigated by Detective Murdoch. The getaway driver for the thieves is killed.  While on scene someone claiming to be Sherlock Holmes shows up and provides some helpful information.  Dr. Ogden figures out that he is actually David Kingsley who at one time was treated for mental illness.  "Sherlock Holmes" appears to have the qualities of the fictional character of the same name such as the ability to "read" an individual or a crime scene.

Murdoch enlists some revealing detective work while investigating a murder at a nudist community.

Murdoch investigates a nanny's disappearance with the so-called real Sherlock Holmes.

Julia discovers a secret about her father upon his death; Brackenreid takes over a murder investigation.

Murdoch and Ogden put aside a personal matter when Nate Desmond is charged with murder.

The young Harry Houdini becomes Murdoch's prime suspect when he investigates a daring robbery-homicide. Meanwhile, Dr. Ogden's sister comes to visit and soon becomes attracted to Murdoch.

Murdoch is called to Station House Five when a decorated constable is murdered and the local detective is ill. Murdoch finds that everyone is ready to blame an elderly Chinaman named Fong Choy because of something to do with his granddaughter, but she is nowhere to be found and Fong Choy won't talk.

Murdoch is called upon to investigate an exceedingly strange murder. The deceased was found inside a room locked from within with no other entrance. But there's more to the case than that – the victim appears to have exploded and burned, yet there is no trace of an explosion or fire. Before Murdoch can proceed with his investigation, the case takes a bizarre turn when old friend and world-renowned inventor Nikola Tesla appears, announcing cryptically that he is "too late."

As the sisters of the Immaculate Conception prepare to put the coffin of elderly Sister Ignatius into her final resting place in the convent’s cemetery, a young novitiate peers into the dug grave and sees something poking out of the dirt – a human hand. Murdoch is called to the scene and his constables lift the bloodied body of the convent’s gardener out of the grave. But a dead body is not the only surprise the convent holds.

After saving his lover Anna from the Black Hand, Detective Murdoch bargains for her life. During his investigation into the murder of a shy librarian with a secret life, he encounters another young woman behaving seductively.

Detective Murdoch and his methods are compromised when one of his colleagues is implicated in a suspicious murder.