Gina puts Connie in a difficult position when she asks her for help behind Elliot's back. Connie must then decide where her loyalties lie. Ric's skills are tested when he has to operate on an obese woman. Matt and Reg find more evidence of drug tampering.

Michael faces his appeal hearing, and uses the opportunity to try to patch things up with Connie, while Sam shares a secret with Chrissie. Lola discovers Leanne's father Steve has been admitted, and becomes convinced he is a drug user.

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Matt tries to raise some money by signing up for clinical trials, after his landlord evicts him over unpaid rent , and Lola is angry when she receives a postcard from her globe-trotting daughter. Donna helps with a drugs audit, but ends up flirting with Bradley.

Connie's heart battles her mind as she wonders if she should stay at Holby. Mark learns to respect the way Tricia wants to handle her cancer.

As the police invstigations into the suspicious deaths continues, Stan Ashleigh is admitted to Holby with heart problems. In theatre Ric Griffin and Diane Lloyd ignore his requested DNR.

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Diane is told to work under Ric's supervision when she is blamed for Helen's death, but she is determined to clear her name and attempts to secretly record Nick confessing to his error. A new assistant general manager starts work at the hospital, and soon invites Donna to the May ball, while Matt gets a second job in the admin department to pay off his debts.

Bradley outlines his cost-cutting plans for the hospital, dividing opinions among the staff, especially when he suggests they could perform more operations to earn a £3million bonus. Joseph returns to the wards, but it is clear his OCD is not under control when he insists on scrubbing his hands repeatedly and fumbles a simple procedure.

Lola makes a drastic decision regarding baby Leeanne's care. Reg wonders if Bradley's intentions towards Donna are honourable. Jac works closely with Joseph.

Jess and Zubin talk and Sean realises she does not love him, so they decide to end their relationship and call off the wedding. Meanwhile, Chrissie persuades Connie to consider Mark for a permanent position, and she says she will interview him that afternoon. Mark says he will go but he later changes his mind and tells Connie he does not want the job. Connie is furious and berates Chrissie. Chrissie storms into the bar where Lisa and Mark are drinking and tells Mark she wants nothing more to do with him. Dominic Fryer starts work as the new teaching consultant but Diane is shocked to see him. One of his students, Emma, turns up, and they argue and she attacks him. Dominic collapses and discovers he has a hernia, so Ric agrees to operate on him later. Diane questions Emma on her relationship with Dominic. She asks if he forced himself on Emma and reveals he did the same to her. Dominic says he wants to be awake during his operation. During the procedure, Dominic and Diane start to argue

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Elliot lets his personal feelings get the better of him when Gina is re-admitted. Sam is put on report but continues to do things on his own terms - will he learn his lesson?

As the reverberations of Jac’s surgery impact around Darwin and beyond, will life on Wyvern Wing ever be the same again? Series Finale

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Jac's determination to have Ric choose her as the new consultant has tragic consequences. Sam bends the rules again and is brought down to earth with a bump. A determined Lola fights to keep Princess at home.