Chemotherapy is taking its toll on Connie, but she remains determined to fly to America to spend Christmas with Grace. However, when she is unexpectedly called into the ED by Hanssen due to a sudden staff shortage, her efforts to battle through the shift place her festive plans - and her life - in danger. Meanwhile, a lonely Sally Hodge (guest star Pam St Clement) returns to the hospital to find an unexpected partner in crime on the ward

One is the Loneliest

William Beck

George Rainsford

Charles Venn

Derek Thompson

Azuka Oforka

Catherine Shipton

Jamie Davis

Amanda Henderson

Jason Durr

Di Botcher

Amanda Mealing

Tony Marshall

Michael Stevenson

Neet Mohan

Charlotte Salt

Michelle Fox

Chelsea Halfpenny

London Calling

Old Flames

As some of the team head to France to help aid efforts at a refugee camp, their experiences leave lasting impressions. At the ED, Connie's world is rocked by sudden news.

Dr Dylan (1)

Conditions at the refugee camp cause a member of the ED team to take drastic action. In Holby, recent events are taking their toll on Jez.

All My Sins (2)

Ethan struggles to put the past behind him, while Iain meets Lily's family, and Dylan's moral compass gets him in a tight spot.

Ghosts

Dylan's plan to reunite Sanosi with his uncle doesn't turn out the way he would have hoped, and Alicia begins her driving lessons with Elle, giving her a crash course.

Collision Course

A familiar face returns under a different guise, while Elle questions how happy she is being a single mother.

Blues and Twos

An anxious Connie focuses on Ethan's consultancy revision while waiting for the results of her tests. Elle meets a potential love interest.

Addicted to Love

Connie struggles to deal with the results of her scans and what it means for her future. Dylan is forced to bring Sanosi into the ED.

Hide and Seek

Connie's denial about her condition reaches crisis point, and she forces Ethan to help her. Alicia's driving test approaches at speed.

Blackmail

Dylan's secret starts to unravel around him as more people get drawn in. Lily's jealousy of Sam threatens her budding relationship with Iain.

Push the Button

A near miss with the discovery of Sanosi leaves Dylan at breaking point. David desperately tried to stop his friend making a terrible mistake.

The Deep End

A new face joins the ED team, while Lily has to make a choice between career and love.

Follow Your Heart

Ethan wrestles with his guilt, while Connie makes a drastic decision over her treatment.

Guilt

The day of Charlotte's christening arrives, and when a flustered Robyn steps into the ED staff room, she finds herself face-to-face with Glen - the terminally ill fiance who jilted her at the altar - very much alive. Naturally, Robyn has a few questions, and Dylan fills in the blanks by flashing back to the morning after Charlie's stag do, when he found a depressed Glen drinking away his woes in a rough karaoke bar. Determined to convince him not to give up on life, Dylan enlists the aid of his feisty old university tutor Zsa Zsa Harper-Jenkinson - an eminent brain surgeon in the US - to assess Glen's case. She reveals that pioneering surgery could save Glen, but the risks are high. However, with Dylan's help, Glen realises the birth of his daughter has given him a new purpose in life and a fresh dream to chase.

The Return

Connie attends her first day of chemotherapy, and in her absence, she places Ethan in charge of the ED. However, his overly thorough approach causes delays, and when the situation gets on top of him, it is up to Duffy to give him a tough love pep talk. Meanwhile, Robyn is dismayed to learn Glen has taken a job as a porter in the department, but he manages to prove his worth dealing with an injured priest with a suspicious fixation on antibiotics

Hardy’s Day’s Work

Connie's illness has a noticeable effect on her work, and even as she continues to brush away help from Charlie, her presence in the ED places her at greater risk of infection. Meanwhile, Ethan shows up late for his practical consultancy exam, and the arrival of new coffee shop worker Polly looks set to signal an improvement in Max's love-life, until he makes an excruciating faux pas while trying to flirt

Crashing

Elle has a shock in store for Jacob. Rash questions his future as a doctor after treating an old girlfriend.

The truth about Connie's illness is out, following her dramatic collapse while at work. As she recovers, she is devastated to hear that her colleagues are aware of her terminal diagnosis. Worse still is the news that her tumour has grown, and complications now mean that her consultant refuses to operate. Discharging herself, Connie persuades Ethan to drive her to London for a second opinion, but when she loses consciousness en route and is rushed into emergency surgery, her put-upon protege faces an agonising wait for news. Meanwhile, back at the ED, Dylan struggles to hold the fort, in the absence of more experienced hands

Max is reunited with James, and old friend from medical school, who enters the ED with his fiancée Aisha after she falls victim to a seemingly spontaneous acid attack. The encounter also gives him cause to re-evaluate his relationship with his estranged wife Zoe, who has arrived at the hospital seeking a reconciliation. Meanwhile, Elle reveals she wants to tell Blake that Jacob is his father, and when the lad is admitted to the department with a compass stuck through his hand, now seems as good a time as any

Elle's son turns up in the ED with his injured friend after going missing all night, schoolteacher Justine faces the consequences of her decision, and Ethan goes for his interview.

Little Fires Everywhere

Dylan struggles to keep his alcoholism under control, as staff on the ED deal with what is suspected to be a case of domestic abuse. Meanwhile, Ethan's first day as Clinical Lead fails to go according to plan, as he finds himself veering wildly from one disaster to another, and he starts to understand the real pressure of leading a team

Drown My Sorrows

Alicia takes matters into her own hands when queuing ambulances put patients in danger, while new F1 Bea gets a rude awakening on her first day.

Keep Afloat

On the day of her son's trial, Elle finds herself looking after the boy he assaulted. Are his new injuries related? Bea's one-night stand leads her to find out Rash's secret.

Judge, Jury, Executioner

Under-pressure Ethan makes a decision that exposes the weaknesses of the ED and gives ammunition to the anonymous blogger. It is Gem's first day as a porter.

Gem’s New Job

The pressures of clinical lead cause Ethan to lose his way as a doctor.

Under Pressure

Dylan struggles to keep his alcoholism a secret from his colleagues. Bea pushes herself to greater heights to impress Ethan.

Drowning

Pressure on Ethan intensifies as he has a day to track down the blog author or it's his neck on the line - is Alicia on the cusp of being outed? Rash must face his fear.

Judas

Rash's new-found confidence is tested by a prisoner, who also leads Gem into danger. Bea goes up against confident F1 Eddie for a coveted training course.

The Competition

The day of Robyn and Glen's wedding arrives, but the groom has a seizure while getting ready at the hotel. Dylan performs a CT scan on him that confirms his cancer has returned, but he keeps quiet and gets through the ceremony, with tragedy striking as the couple depart for their honeymoon. Rash treats a woman suffering from anxiety after the death of her fiance

Petals (1)

Glen faces a heartbreaking decision on what should have been the happiest day of his life.

Wilted (2)

Ethan's pregnant patient holds a nasty surprise.

Surprise

Bea's day goes from bad to worse professionally and privately. Will it end sourly? How will Leigh-Anne cope with Ethan's confession?

Confession

Ethan is in danger of crossing a line with Leigh-Anne, while Robyn throws away a present from Glen after he questions whether she is fit to be in work. Bea wakes up in an alley calling for help, which comes in the form of nightclub bouncer Johnny, who initially refuses treatment for his own nasty cut

The Line

Connie is back, and she has a big idea for the ED - but Charlie is not convinced.

Beauchamp in Charge

Iain and Sam, neck-deep in water and running out of time, are forced to make a life-changing decision. When Bea's secrets are revealed, she finally has to confront her demons.

Rising Water

Iain and Sam find a confused woman with deep lacerations to her head wandering the streets, and when they take her into the ED, Connie instantly recognises her as a friend from chemotherapy. Bea struggles to regain her confidence on her first day back at work, while Alicia and Ethan have a heart-to-heart and agree to be friends again.

Forgive Me

Alicia struggles to process the events of her night with Eddie, and collapses at work after refusing to take a break. Just as she starts to open up to Ethan about her problems, Elle interrupts. A girl breaks out of her house to run away with her boyfriend, but the coach they are travelling on crashes, while Jacob is determined to get Blake to study.

Shattered

Eddie realises Alicia is scared of him after discovering that she has swapped all her shifts to avoid him. Meanwhile, Bea receives a phone call about her dad and leaves work to pick him up from the police station, and Sam and Jacob discuss which of the ED staff she would be able to beat in a boxing match.

Hit Me Hard

With Dylan nowhere to be found, Connie and Elle are forced to work together to pitch for funding for a new trauma centre. With both women struggling to hide their resentment of each other, their relationship hits rock bottom. Elsewhere, Bea grows concerned for Alicia, while Gem and Rash are tasked with looking after Connie's goldfish.

A Day’s Work

Struggling to keep a lid on her emotions following her night with Eddie, Alicia pushes Ethan away. She then has to deal with Leigh-Anne, who arrives in the ED with her son Kiegan, but a shocking confession from Ethan leaves her feeling even more alone. Connie returns and immediately notices that someone has killed her goldfish and replaced it. With Elle's encouragement, Connie has some fun waiting for the culprits to reveal themselves and puts the pressure on. Elsewhere, Robyn asks for more overtime due to her parking fines.

Bottle and Boom

New paramedic Ruby is pushed to her limits on her first day with Iain and Sam. She expertly revives an overdosed drug addict, who repays her by punching her in the face. Alicia struggles to work with Eddie and her angry outbursts increase, but she opens up when Bea confronts her with concerns about her behaviour. Elsewhere, it's the 70th anniversary of the NHS and Noel wants to celebrate with homemade stickers, while Sam apologises to Jacob for standing him up.

Bright Spark

Bea tries to give Alicia the help she needs following the attack, while Eddie tries to rebuild their relationship - only to be told they are purely professional colleagues. Jacob lies to Sam and tells her that Blake knows about their relationship. Elsewhere, after overhearing Sam express her doubts that she will last another shift, Ruby attempts to build bridges with her colleagues and patients. A father and son are brought in with injuries they refuse to explain, raising suspicions of abuse - but it is not clear who is the abuser and who the victim.

Complexes

Alicia finds herself on a collision course with Bea after deciding not to report her rape.

When Life Turns Upside Down

Alicia plucks up her courage to tell the police that she has been raped. Eddie accompanies the paramedics who are called out to treat Jon's wife after she suffers serious burns - and is arrested on his return to the hospital. Bea leaves to make a fresh start in Paris, and Alicia receives an unwelcome visit that has devastating consequences.

Through the Looking Glass

Drama series about the staff and patients at Holby City Hospital's emergency department, charting the ups and downs in their personal and professional lives.

One is the Loneliest

Seasons46

Season 32 Episodes44

Cast17

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Episode Summary