David tracks down his estranged wife, Kate, to get her help in saving their 10-year-old son who is dying of leukaemia. Meanwhile, Zoe has had to go home sick, leaving Ash to deal with the continuing flu epidemic.

Ostrich Syndrome

William Beck

Derek Thompson

Azuka Oforka

Matt Bardock

Daniel Anthony

Sunetra Sarker

Amanda Henderson

Patrick Robinson

Tony Marshall

Suzanne Packer

Charles Dale

Jane Hazlegrove

Christine Tremarco

Oliver Coleman

Charlotte Salt

Michael Obiora

Alex Walkinshaw

Gemma-Leah Devereux

Though Lovers Be Lost

If Not for You

Zoe's first day as the ED'S clinical lead gets off to a trying start when the team are faced with dealing with the aftermath of a tunnel collapse at a music festival.

Kansas

Tamsin faces a ghost from her past when she and Jeff attend a call out at a lap dancing club. Sam attempts to unravel the mystery of a patient with amnesia.

Cuckoo's Nest

Sam and Tom are pushed to their limits when a female cage fighter insists on fighting against their advice, and a wedding is threatened to be ruined by devastating news.

Rock, Paper, Scissors

Dylan and Tess must treat an agitated pregnant woman, while Fletch tries to unravel the relationship between a teenage girl and her swimming coach.

An Amateur Sport

The team is put to the test when Holby is hit by severe weather, and the stress of work and dealing with a face from the past leads Big Mac's health to take a dangerous turn.

I'll See You in My Dreams

Medical drama. Fletch plays a practical joke on Lloyd after a staff night out, and Dylan attempts to teach a medical student about the dangers of alcohol abuse.

Evolve or Be Extinct

The team deal with an accident at a troubled small business, and a young businessman with heart problems is demanding staff find his missing phone

Tough Love

Zoe oversteps the line when she attempts to help a vulnerable young woman, and Mac gets into serious trouble on his first day back when a patient with Alzheimer's appears to have swallowed some cleaning fluid.

The Kindness of Strangers

Zoe struggles to deal with the fallout of a suspected E. coli outbreak, and Dylan is touched by an elderly patient who has lost his beloved wife.

Harvest Festival (1)

Zoe and the ED reap the fallout from the E-coli outbreak and things go from bad to worse for farmer Rob.

Seeing in the Dark (2)

Dylan deals with a woman whose pregnancy is not all it seems, and teenager Angel is desperate to get some cash together to pay off her bullies.

When Love Breaks Down

Tamzin's decision not to treat an aggressive patient has serious repercussions, and Tom and Sam differ over how to approach a family with a dark secret.

Out of the Blue

A family are shocked to find out an intruder isn't all he seems to be, and a woman finds out she's the heir to her nasty aunt's fortune.

Sixteen Candles

As Charlie and Big Mac prepare for the ED party, Dylan's suspicions reach boiling point.

My Aim Is True

A secret puts a strain on Jeff and Tamzin's friendship and makes life difficult for Dixie.

The Blame Game

Tensions once again rise between Tom and Dominic as they argue over the treatment of a baby with severe hypothermia, and Dylan finally admits that he has not moved on from Sam.

I Saw Mommy Killing Santa Claus

Four student nurses receive a baptism of fire on their first shift in the ED.

Rabbits in Headlights

Zoe is concerned that Jordan is not facing up to the severity of Yvonne's condition.

Smoke and Mirrors

Jordan fights to keep his girlfriend's life support machine switched on but when an ill young woman arrives in the ED, he's forced to reconsider his motives.

No Other Medicine

It is the day of Yvonne Rippon's funeral, and Nylon gets Jordan to visit him.

Broken Heart Syndrome

Jordan is called on to save the life of the person who killed his girlfriend.

Life Goes On

New doctor Ash hits the ground running when he treats a patient with suspected rabies, and Aoife is forced to take control when ex-boyfriend Craig arrives in Holby.

Jeff must persuade David to act in his son's best interests, Fletch is determined to help an elderly man in love, and Zoe returns from sick leave and clashes with Ash.

Big Mac thinks he may have finally found the woman of his dreams but when she mistakes him for a doctor he doesn't set her straight. Ash clashes with Zoe when he carries out a risky procedure without telling her.

Brave New World

Ash and Zoe struggle to make a teenage boy accept the severity of his father's condition, while Linda helps a pregnant woman cope with her waster boyfriend.

Cross Roads

Jeff is caught up in a marital dispute, and Robyn breaches patient confidentiality.

With and Without You

Robyn has to try and save her friend's life when a day at the fairground goes badly wrong.

And the Walls Come Tumbling Down

Tom helps a young man with a troubled home life. Jamie treats a young boxer.

Punch Drunk Love

Zoe and Ash must work together to reunite two schoolgirls injured during a science exam.

Hidden (1)

Zoe goes out of her way to help and protect a young girl who she believes is at risk of female genital mutilation. Fletch deals with a man who needs to take responsibility for his health and lifestyle.

Unsilenced (2)

Jeff is distressed when his father and sister are involved in a car accident.

Family Matters

When hoodies raid an off-licence, a family must pull together to stop the gang's reign.

Human Resources

Ash deals with his daughter's admission to the ED after being hit by a drunken police driver, while Tom's judgement is called into question when a baby he has discharged nearly dies.

The Morning After

Linda's nursing experience enables her to see the bigger picture concerning a patient.

Isolated Incident

Tom is determined to show that a previous misdiagnosis isn't affecting his confidence.

The Milk of Human Kindness

When Tess witnesses a stabbing she becomes involved with the attacker and victim.

Love Is the Drug

Lloyd tries to uncover the truth about a cannabis factory on his final day as a nurse.

You Always Hurt the One You Love

Tom faces a dilemma of truth and confidentiality over the paternity of a baby.

Garage Flowers

Ash and Zoe have to protect a local shopkeeper who has been harassed by unruly kids.

What Goes Up

Tom and Sam clash over the best course of action when a mother can no longer cope.

Letting Go

When Marcus is mugged, Sam and Fletch work together to reveal who the real victim is.

A History of Violence

Tom is on a personal visit to a prison when unrest breaks out and trouble ensues.

Secrets and Lies (1)

Arthur and Chantelle struggle to cope in the aftermath of the mugging.

Mistakes Happen (2)

Drama series about the staff and patients at Holby City Hospital's emergency department, charting the ups and downs in their personal and professional lives.

Ostrich Syndrome

Seasons46

Season 27 Episodes44

Cast18

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Episode Summary