Ranked #5 of 5 in Season 2•−0.3 vs season avg
While Martin continues to struggle with his blood phobia, a mermaid washes ashore in Port Wenn to the amazement of everyone in town. Meanwhile, Judith, a well-meaning townsperson (guest star Andrea Martin), creates havoc while on prescribed oxygen, Louisa continues to see Martin's girlfriend Eden
Josh Charles
Dr. Martin Best
Abigail Spencer
Louisa Glasson
Josh Segarra
Sheriff Mark Mylow
Cree
Elaine Denham
Annie Potts
Aunt Joan
Stephen Spinella
Greg Garrison
Jason Veasey
George Brady
Eliza Coupe
Eden Montgomery
Liz Tuccillo
Writer
Nancy Hower
Director
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"Be Careful What You Fish For" is episode 1 of Best Medicine season 2. It scored 8.1/10 from 249 votes, ranking #5 of 5 episodes this season (season average 8.4). Directed by Nancy Hower and written by Liz Tuccillo, it aired on September 20, 2026.
